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Results: The median follow-up time for the entire group was 27 months (ranging 7 to 80 months). The 3-year overall survival (OS) rate was 85%, and the 3-year local failure-free rate (LFFR), distant failure-free rate (DFFR) and disease-free survival (DFS) rates were 93%, 81%, and 73%, respectively. A positive correlation between GTVnx or GTVp volume and T stage was observed (both P42.7 cm3 (all P
After RT, all patients were assessed every 3 months during the first 2 years, and every 6 months thereafter until death. All events were measured from the date of completion of radiation therapy until documented treatment failure or the last follow-up visit. The primary end-point was: local failure-free rate (LFFR-persistence/recurrence at nasopharynx). The second end-points were overall survival (OS-death due to any cause), disease-free survival (DFS-staying free of disease after radiotherapy), and distant failure-free rate (DFFR-disease metastasis at distant sites).
Results: The median follow-up time was 40 months, ranging from 5 to 69 months. The 3-year disease-free survival (DFS), overall survival (OS), locoregional recurrence-free survival (LRRFS), and distant metastasis-free survival (DMFS) rates were 80.8, 90.0, 91.6, and 87.4%, respectively. The most frequent acute grade 3/4 adverse events were leukopenia (66.8%), neutropenia (55.8%), mucositis (41.1%), thrombocytopenia (27.0%), and anemia (14.7%). 2b1af7f3a8